SCHEMBL5560846

SCHEMBL5560846

CC(O)(C=O)Cc1ccc(OCCOS(C)(=O)=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.38
MMP1 P03956 3/20 0.36
MMP9 P14780 3/20 0.36
MMP13 P45452 3/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
S1PR1 P21453 1/20 0.36
PTPN1 P18031 1/20 0.36
ACACB O00763 1/20 0.36
EBP Q15125 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5560855 0.82 PPARA (0.41) PPARAALDH1A1LMNAACACB
SCHEMBL788296 0.81 SMN1; SMN2 (0.50) ALDH1A1LMNAACACBEBPSIGMAR1
SCHEMBL19644362 0.81 SMN1; SMN2 (0.50) ALDH1A1LMNAACACBEBPSIGMAR1
SCHEMBL10455828 0.81 LMNA (0.39) PPARAALDH1A1LMNAACACBEBP
SCHEMBL9614864 0.80 SMN1; SMN2 (0.48) ALDH1A1LMNAACACBEBPSIGMAR1
SCHEMBL6027401 0.78 NR5A1 (0.51) S1PR1
SCHEMBL10454958 0.77 SMN1; SMN2 (0.46) PPARAALDH1A1LMNAACACBSMN1; SMN2
SCHEMBL9575718 0.77 ALDH1A1 (0.39) PPARAALDH1A1LMNAACACBEBP
SCHEMBL9575749 0.77 ACACB (0.38) PPARAALDH1A1LMNAACACBEBP
SCHEMBL3975354 0.77 THRA (0.38) ALDH1A1LMNAACACBEBPSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330295-B1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION, ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND CURED PRODUCT FUJIFILM CORP (JP) 2019-08-21 EP disclosed
EP-3330295-A1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION, ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND CURED PRODUCT FUJIFILM Corporation (JP) 2018-06-06 EP disclosed
US-20180148519-A1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION, ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND CURED PRODUCT FUJIFILM CORPORATION (JP) 2018-05-31 US disclosed
EP-1451615-B1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES NOVARTIS AG (CH) 2007-11-14 EP disclosed
US-6878399-B2 Method for modifying the surface of biomedical articles NOVARTIS AG (CH) 2005-04-12 US disclosed
EP-1451615-A1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES Novartis AG (CH) 2004-09-01 EP disclosed
US-20030219533-A1 Method for modifying the surface of biomedical articles NOVARTIS AG (CH) 2003-11-27 US disclosed
WO-2003042724-A1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES NOVARTIS AG (CH) 2003-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180148519-A1 PHOTOPOLYMERIZATION INITIATOR COMPOSITION, ACTIVE ENERGY RAY-CURABLE COMPOSITION, AND CURED PRODUCT PARP1, PARP9, PARP4 PPARA 3522/4885MMP1 2635/4885MMP9 2201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.