Sugi Predict

Sugi Predict / Compounds / SCHEMBL55610

SCHEMBL55610

SCHEMBL55610

CC(C)(C)OC(=O)N1CC(O)C[C@@H]1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.59
▸ CYP1A2 P05177 1/20 0.52
▸ POLB P06746 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ CHRM2 P08172 1/20 0.46
▸ CHRM1 P11229 1/20 0.46
▸ CHRM3 P20309 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.43
▸ NR1H2 P55055 1/20 0.40
▸ HTRA1 Q92743 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ MME P08473 1/20 0.37
▸ BTK Q06187 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ HSD11B1 P28845 1/20 0.35
▸ RIPK1 Q13546 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5200883 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL764093 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL242328 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL116439 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL55611 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL873280 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL193111 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL312687 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL4275881 0.98 ATM (0.57) ATMCYP1A2POLBCYP3A4CYP2C19
Ammonia Solution, Strong SCHEMBL29062671 0.98 ATM (0.57) ATMCYP1A2POLBCYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 — — CN claimed
EP-4695236-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 — — US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 — — US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 — — EP disclosed
US-12325701-B2 YKL-40 inhibitors and their therapeutic MOLECURE S.A. (PL) 2025-06-10 — — US disclosed
WO-2024216094-A1 SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. (US) 2024-10-17 — — WO disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 — — US disclosed
CN-111989321-B KRAS G12C inhibitors 米拉蒂治疗股份有限公司 2024-05-14 — — CN disclosed
CN-117999261-A Novel compounds and their use in the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-05-07 — — CN disclosed
US-20020072586-A1 Chiral peptide nucleic acids ISIS INNOVATION LIMITED (GB) 2002-06-13 — — US disclosed
EP-1213281-A1 NOVEL AMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-06-12 — — EP disclosed
US-6399629-B1 PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY MICROCIDE PHARMACEUTICALS, INC. 2002-06-04 — — US disclosed
WO-2002042316-A2 PNA ANALOGUES PANTHECO A/S (DK) 2002-05-30 — — WO disclosed
EP-0618810-B1 BRADYKININ ANTAGONIST PEPTIDES SCIOS NOVA INC (US) 2001-07-04 — — EP disclosed
US-5385889-A Substitution of L-proline at the 7-position of the peptide hormone with a D-configuration hydroxyproline ether or thioether converts agonist into antagonist SCIOS NOVA INC. (US) 1995-01-31 — — US disclosed
EP-0618810-A4 BRADYKININ ANTAGONIST PEPTIDES. SCIOS NOVA INC (US) 1994-12-07 — — EP disclosed
EP-0618810-A1 BRADYKININ ANTAGONIST PEPTIDES SCIOS NOVA INC. (US) 1994-10-12 — — EP disclosed
WO-1992018156-A1 BRADYKININ ANTAGONIST PEPTIDES NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) 1992-10-29 — — WO disclosed
US-4424312-A COPOLYMERIZING N-ACRYLOYL-4-(DIPHENYLPHOSPHINO)-2--(DIPHENYLPHOSPHINOMETHYL)PYRROLIDINE, RHODIUM COMPLEX POLYMER SCIENCES CORPORATION (US) 1984-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH ATM 4455/4885CYP1A2 2802/4885POLB 2725/4885
US-12325701-B2 YKL-40 inhibitors and their therapeutic CHI3L1, CHI3L2, CHIA ATM 2548/4885CYP1A2 4830/4885POLB 4381/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 ATM 4453/4885CYP1A2 4720/4885POLB 2834/4885
US-20020072586-A1 Chiral peptide nucleic acids POLL, HNRNPL, HLA-B ATM 4101/4885CYP1A2 4702/4885POLB 43/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH ATM 4377/4885CYP1A2 2591/4885POLB 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.