SCHEMBL242328

SCHEMBL242328

CC(C)(C)OC(=O)N1C[C@@H](O)C[C@H]1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.59
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C19 P33261 1/20 0.52
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
CHRM3 P20309 1/20 0.46
HSD17B10 Q99714 1/20 0.43
NR1H2 P55055 1/20 0.40
HTRA1 Q92743 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MME P08473 1/20 0.37
BTK Q06187 1/20 0.36
ALDH1A1 P00352 1/20 0.35
HSD11B1 P28845 1/20 0.35
RIPK1 Q13546 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5200883 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL764093 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL55610 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL116439 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL55611 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL873280 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL193111 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL312687 1.00 ATM (0.59) ATMCYP1A2POLBCYP3A4CYP2C19
SCHEMBL4275881 0.98 ATM (0.57) ATMCYP1A2POLBCYP3A4CYP2C19
Ammonia Solution, Strong SCHEMBL29062671 0.98 ATM (0.57) ATMCYP1A2POLBCYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060926-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SAIL BIOMEDICINES INC (US) 2026-03-05 US disclosed
US-12534470-B2 DNA polymerase IIIC inhibitors and use thereof Acurx Pharmaceuticals, Inc. (US) 2026-01-27 US disclosed
US-12528814-B2 Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof NURIX THERAPEUTICS, INC. (US) 2026-01-20 US disclosed
EP-4678238-A2 ARGINASE INHIBITORS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2026-01-14 EP disclosed
US-12522593-B2 Azacycloalkyl carbonyl cyclic amine compound ALIVEXIS, INC. (JP) 2026-01-13 US disclosed
US-20260001875-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE UNIV DUNDEE (GB) 2026-01-01 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-20250360141-A1 PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2025-11-27 US disclosed
US-20250313578-A1 Arginase Inhibitors and Methods of Use Thereof ASTRAZENECA AB (SE) 2025-10-09 US disclosed
US-12435061-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2025-10-07 US disclosed
US-5385889-A Substitution of L-proline at the 7-position of the peptide hormone with a D-configuration hydroxyproline ether or thioether converts agonist into antagonist SCIOS NOVA INC. (US) 1995-01-31 US disclosed
EP-0618810-A4 BRADYKININ ANTAGONIST PEPTIDES. SCIOS NOVA INC (US) 1994-12-07 EP disclosed
EP-0618809-A1 BRADYKININ TYPE PEPTIDES SCIOS NOVA INC. (US) 1994-10-12 EP disclosed
EP-0618810-A1 BRADYKININ ANTAGONIST PEPTIDES SCIOS NOVA INC. (US) 1994-10-12 EP disclosed
EP-0618809-A4 BRADYKININ TYPE PEPTIDES. SCIOS NOVA INC (US) 1994-07-28 EP disclosed
EP-0560269-A1 Substituted pyrrolidine derivatives as HIV protease inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed
WO-1992018156-A1 BRADYKININ ANTAGONIST PEPTIDES NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) 1992-10-29 WO disclosed
WO-1992018155-A1 BRADYKININ TYPE PEPTIDES NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) 1992-10-29 WO disclosed
US-4902684-A Benzazepine and benzothiazepine derivatives E. R. SQUIBB & SONS, INC. (US) 1990-02-20 US disclosed
WO-1989012633-A1 BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES E.R. SQUIBB & SONS, INC. (US) 1989-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435061-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 ATM 3391/4885CYP1A2 202/4885POLB 1659/4885
US-12528814-B2 Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof IRAK1, IRAK2, IRAK3 ATM 800/4885CYP1A2 4523/4885POLB 1592/4885
US-20250313578-A1 Arginase Inhibitors and Methods of Use Thereof ARG1, ARG2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ATM 4098/4885CYP1A2 234/4885POLB 1812/4885
US-20260060926-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SGMS1, NPC1L1, SGMS2 ATM 3641/4885CYP1A2 4683/4885POLB 3115/4885
US-12534470-B2 DNA polymerase IIIC inhibitors and use thereof POLR1A, POLR2H, POLN ATM 3788/4885CYP1A2 1600/4885POLB 4/4885
US-20260001875-A1 AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE LRRK2, XIAP, PARK7 ATM 622/4885CYP1A2 4251/4885POLB 2700/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 ATM 4453/4885CYP1A2 4720/4885POLB 2834/4885
US-20250360141-A1 PYRIDINE DERIVATIVES WITH N-LINKED CYCLIC SUBSTITUENTS AS cGAS INHIBITORS CGAS, GLS2, GMPS ATM 351/4885CYP1A2 647/4885POLB 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.