Butane

Butane

SCHEMBL5564092

CCCC.OOCc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 4/20 0.48
IDO1 P14902 1/20 0.46
TP53 P04637 1/20 0.46
CETP P11597 3/20 0.44
AGXT P21549 1/20 0.44
SLC6A2 P23975 2/20 0.43
SLC6A3 Q01959 2/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
PTGS1 P23219 1/20 0.43
CYP2C19 P33261 1/20 0.43
PTGS2 P35354 1/20 0.43
HIF1A Q16665 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
MAPK1 P28482 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
CYP3A4 P08684 1/20 0.43
LIPE Q05469 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28253955 0.90 TSHR (0.60) TSHRALDH1A1IDO1AGXTSLC6A2
SCHEMBL111650 0.90
Methylamine SCHEMBL28341679 0.88 IDO1 (0.54) TSHRALDH1A1IDO1TP53AGXT
Fluoride SCHEMBL27339282 0.87 TSHR (0.57) TSHRALDH1A1IDO1AGXTSLC6A2
SCHEMBL4363424 0.87 TSHR (0.57) TSHRALDH1A1IDO1AGXTSLC6A2
Water SCHEMBL2348698 0.87 TSHR (0.57) TSHRALDH1A1IDO1AGXTSLC6A2
Hydrochloric Acid SCHEMBL38661600 0.87 TSHR (0.57) TSHRALDH1A1IDO1AGXTSLC6A2
Toluene SCHEMBL6346718 0.84 TSHR (0.50) TSHRALDH1A1IDO1AGXTSLC6A2
Bicarbonate SCHEMBL9348277 0.83 ALDH1A1 (0.56) TSHRALDH1A1IDO1SLC6A2SLC6A3
Ethaneperoxoic Acid SCHEMBL27833212 0.80 ALDH1A1 (0.64) TSHRALDH1A1SLC6A2SLC6A3PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6936735-B2 Photostable cationic organic sunscreen compounds and compositions obtained therefrom EMD CHEMICALS, INC. (US) 2005-08-30 US claimed
US-20040057911-A1 Photostable cationic organic sunscreen compounds and compositions obtained therefrom EMD CHEMICALS INC. 2004-03-25 US claimed
US-7301038-B2 Process for preparing alkylene oxide (epoxid, oxirane) SHELL OIL COMPANY (US) 2007-11-27 US disclosed
US-7294726-B2 Process for preparing alkylene oxide SHELL OIL COMPANY (US) 2007-11-13 US disclosed
CN-1301950-C Novel vitamin D analogues GALDERMA RES & DEV (FR) 2007-02-28 CN disclosed
CN-1678556-A Novel vitamin D analogues GALDERMA RES & DEV (FR) 2005-10-05 CN disclosed
EP-0948403-B1 HETEROGENEOUS CATALYST REGENERATION ARCO CHEM TECH (US) 2005-02-09 EP disclosed
EP-1490347-A1 PROCESS FOR PREPARING ALKYLENE OXIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2004-12-29 EP disclosed
US-20040210067-A1 Process for preaparing alkylene oxide(epoxid, oxirane) SHELL OIL COMPANY 2004-10-21 US disclosed
EP-1392668-B1 PROCESS FOR PREPARING ALKYLENE OXIDE (EPOXID, OXIRANE) SHELL INT RESEARCH (NL) 2004-09-29 EP disclosed
EP-1392668-A1 PROCESS FOR PREPARING ALKYLENE OXIDE (EPOXID, OXIRANE) SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2004-03-03 EP disclosed
EP-1204653-B1 PROCESS FOR PREPARING ALKYLENE OXIDE SHELL INT RESEARCH (NL) 2003-01-29 EP disclosed
WO-2002090340-A1 PROCESS FOR PREPARING ALKYLENE OXIDE (EPOXID, OXIRANE) SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2002-11-14 WO disclosed
EP-1204653-A1 PROCESS FOR PREPARING ALKYLENE OXIDE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 2002-05-15 EP disclosed
US-6365761-B1 REACTIVATION OF HETEROGENEOUS EPOXIDATION PARTICLES, CONTAINED IN A REACTORS CONNECTED IN A SERIES FOR CONTINOUS PROCESSING BY REPOSITIONING AND CONTACTING WITH WARM EFFLUENT FROM THE PREVIOUS REACTOR SHELL OIL COMPANY 2002-04-02 US disclosed
WO-2001012617-A1 PROCESS FOR PREPARING ALKYLENE OXIDE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2001-02-22 WO disclosed
EP-0948403-A1 HETEROGENEOUS CATALYST REGENERATION ARCO Chemical Technology, L.P. (US) 1999-10-13 EP disclosed
US-5916835-A RESTORED BY WASHING WITH WATER, ALCOHOL, ETHER, NITRILE, ESTER, AROMATIC HYDROCARBON, KETONE ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1999-06-29 US disclosed
US-5798313-A HEATING TO 700 DEGREES C. IN OXYGEN STREAM; TITANIA ON SILICA EPOXIDATION CATALYST ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-08-25 US disclosed
WO-1998028072-A1 HETEROGENEOUS CATALYST REGENERATION ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040057911-A1 Photostable cationic organic sunscreen compounds and compositions obtained therefrom CYC1, RER1, COL2A1 TSHR 4716/4885ALDH1A1 599/4885IDO1 1619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.