Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566530 | 0.81 | F10 (0.46) | ALDH1A1L3MBTL1MAPTF10HTT | |
| SCHEMBL2423853 | 0.79 | MAPK9 (0.54) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL4965751 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL2428407 | 0.72 | MAPK9 (0.53) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL6021743 | 0.71 | POLB (0.50) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL5248869 | 0.71 | L3MBTL1 (0.75) | ALDH1A1LMNAL3MBTL1SMN1; SMN2HTT | |
| SCHEMBL5564830 | 0.69 | L3MBTL1 (0.45) | ALDH1A1LMNAL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7435212 | 0.66 | MAPK9 (0.48) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL2422959 | 0.66 | MAPK9 (0.52) | ALDH1A1LMNAL3MBTL1SMN1; SMN2NPSR1 | |
| SCHEMBL2419998 | 0.66 | MAPK9 (0.53) | ALDH1A1LMNASMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850846-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | Laboratoires Serono SA (CH) | 2007-11-07 | — | — | EP | disclosed |
| WO-2005097116-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-10-20 | — | — | WO | disclosed |