Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428407 | 0.92 | MAPK9 (0.53) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL2421342 | 0.90 | MAPK9 (0.56) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL2423853 | 0.85 | MAPK9 (0.54) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL7435285 | 0.82 | BCL2 (0.40) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL3480648 | 0.82 | MAPK9 (0.60) | MAPK9MAPK10ALDH1A1LMNAMEN1 | |
| SCHEMBL6021743 | 0.81 | POLB (0.50) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL4965751 | 0.80 | SMN1; SMN2 (0.53) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL3480113 | 0.80 | MAPK9 (0.54) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL2426839 | 0.79 | MEN1 (0.53) | MAPK9MAPK10ALDH1A1LMNAPOLB | |
| SCHEMBL7704876 | 0.78 | ALDH1A1 (0.57) | MAPK9MAPK10ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |