Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564833 | 0.81 | ALDH1A1 (0.44) | F10MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL3479895 | 0.80 | MAPK9 (0.53) | F10MAPTALDH1A1TDP1POLB | |
| SCHEMBL5566527 | 0.72 | F10 (0.50) | F10MAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7894669 | 0.72 | MAPK9 (0.59) | F10MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL7894689 | 0.70 | MAPK9 (0.55) | F10MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL7894704 | 0.70 | MAPK9 (0.55) | F10MAPTALDH1A1TDP1POLB | |
| SCHEMBL2420177 | 0.69 | MAPK9 (0.60) | MAPTALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL2425275 | 0.69 | MAPK9 (0.53) | F10MAPTALDH1A1POLBL3MBTL1 | |
| SCHEMBL7435815 | 0.66 | MAPK9 (0.55) | F10MAPTALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2422619 | 0.66 | MAPK9 (0.52) | MAPTALDH1A1TDP1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1850846-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | Laboratoires Serono SA (CH) | 2007-11-07 | — | — | EP | disclosed |
| WO-2005097116-A1 | COMPOSITION COMPRISING A JNK INHIBITOR AND CYCLOSPORIN | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-10-20 | — | — | WO | disclosed |