Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327259 | 0.87 | DGAT1 (0.42) | DGAT1ALDH1A1GAAMGAMSI | |
| SCHEMBL9752808 | 0.83 | DGAT1 (0.39) | DGAT1ALDH1A1POLBMMP8TSHR | |
| SCHEMBL4791578 | 0.81 | DGAT1 (0.38) | DGAT1ALDH1A1POLBMMP8TSHR | |
| SCHEMBL17617189 | 0.80 | ALDH1A1 (0.36) | DGAT1ALDH1A1GAAMGAMSI | |
| SCHEMBL17617140 | 0.80 | ALDH1A1 (0.36) | DGAT1ALDH1A1GAAMGAMSI | |
| SCHEMBL6229413 | 0.79 | TSHR (0.37) | DGAT1ALDH1A1GAAMGAMSI | |
| SCHEMBL3169320 | 0.79 | DGAT1 (0.37) | DGAT1ALDH1A1POLBMMP8TSHR | |
| SCHEMBL2316349 | 0.79 | MMP8 (0.47) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL8899156 | 0.79 | TSHR (0.37) | DGAT1ALDH1A1GAAMGAMSI | |
| SCHEMBL13051348 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419407-B1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN SA (GR) | 2012-11-14 | — | — | EP | disclosed |
| EP-2419407-A1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | Pharmathen S.A. (GR) | 2012-02-22 | — | — | EP | disclosed |
| US-20120035374-A1 | PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010118757-A1 | IMPROVED PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035374-A1 | PROCESS FOR THE PREPARATION OF FLUVASTATIN AND SALTS THEREOF | HMGCR, CETP, PCSK9 | DGAT1 1283/4885ALDH1A1 2713/4885GAA 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.