SCHEMBL5565486

SCHEMBL5565486

CCC(O)(O)Nc1cccc(NC(=O)NCCN(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.47
HTT P42858 2/20 0.47
POLB P06746 1/20 0.47
MEN1 O00255 1/20 0.47
EPHX1 P07099 5/20 0.44
ATM Q13315 6/20 0.43
EPHX2 P34913 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6719494 0.87 MAPT (0.50) MAPTKMT2AHTTPOLBMEN1
SCHEMBL15601909 0.79 MAPT (0.53) MAPTKMT2AHTTPOLBMEN1
SCHEMBL5779764 0.78 KMT2A (0.52) MAPTKMT2AHTTPOLBMEN1
SCHEMBL5565031 0.78 CNR1 (0.55) MAPTKMT2AHTTPOLBMEN1
SCHEMBL2597849 0.76 HTT (0.64) MAPTKMT2AHTTPOLBMEN1
SCHEMBL6719504 0.76 MAPT (0.49) MAPTKMT2AHTTPOLBMEN1
SCHEMBL5565500 0.75 MAPT (0.48) MAPTKMT2AHTTPOLBMEN1
SCHEMBL6719499 0.75 HTT (0.50) MAPTKMT2AHTTPOLBMEN1
SCHEMBL5565491 0.74 MEN1 (0.46) MAPTKMT2AHTTPOLBMEN1
SCHEMBL5566673 0.73 SMN1; SMN2 (0.49) MAPTKMT2AHTTPOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229479-B2 Method of coloring porous material CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-06-12 US disclosed
US-20060162095-A1 Method of colouring porous material CIBA SPECIALTY CHEMICALS CORP. 2006-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060162095-A1 Method of colouring porous material ACR, HLA-C, TYR MAPT 2284/4885KMT2A 3603/4885HTT 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.