Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CASR | P41180 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565500 | 0.89 | MAPT (0.48) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL5565491 | 0.80 | MEN1 (0.46) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL5779764 | 0.79 | KMT2A (0.52) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL5565031 | 0.79 | CNR1 (0.55) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL6719494 | 0.78 | MAPT (0.50) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL15601909 | 0.77 | MAPT (0.53) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL2597849 | 0.77 | HTT (0.64) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL5565486 | 0.76 | MAPT (0.51) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL5566673 | 0.74 | SMN1; SMN2 (0.49) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL6719499 | 0.73 | HTT (0.50) | MAPTMEN1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673966-B2 | FOR USE IN HAIR COLORING FORMULATIONS | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| US-20020100127-A1 | Novel coupler for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020100127-A1 | Novel coupler for use in oxidative hair dyeing | CBR1, CBR3, PYCR1 | MAPT 4628/4885MEN1 4000/4885KMT2A 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.