Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200282 | 0.85 | MME (0.52) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL28447871 | 0.85 | MME (0.52) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL8299830 | 0.83 | PPARG (0.51) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL346889 | 0.81 | MME (0.51) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL3923887 | 0.80 | PPARG (0.56) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL3923892 | 0.80 | PPARG (0.56) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL18351661 | 0.80 | PPARG (0.56) | MMEPPARGACEFOLH1NAALAD2 | |
| SCHEMBL12984801 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNA | |
| SCHEMBL290549 | 0.80 | PPARG (0.76) | PPARG | |
| SCHEMBL2217249 | 0.80 | PPARG (0.76) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1842542-A1 | Novel PPAR ligands that do not cause fluid retention, edema or congestive heart failure | Bethesda Pharmaceuticals, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |