Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566828 | 0.90 | ALDH1A1 (0.45) | NLRP3ALDH1A1GAAPGRPTGS1 | |
| SCHEMBL6022886 | 0.89 | NLRP3 (0.42) | NLRP3ALDH1A1GAAPGRPTGS1 | |
| SCHEMBL27489719 | 0.84 | ALDH1A1 (0.49) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL4801387 | 0.77 | NLRP3 (0.50) | NLRP3GABRA1GABRB2ALDH1A1GAA | |
| SCHEMBL2397978 | 0.77 | ALDH1A1 (0.45) | NLRP3GABRA1GABRB2ALDH1A1GAA | |
| SCHEMBL13893720 | 0.76 | GABRA1 (0.43) | NLRP3GABRA1GABRB2ALDH1A1GAA | |
| SCHEMBL77829 | 0.75 | ALDH1A1 (0.56) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL132875 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL8536538 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| Bromide SCHEMBL6851419 | 0.73 | ALDH1A1 (0.54) | ALDH1A1GAAPGRPTGS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651034-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-05-03 | — | — | EP | claimed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | claimed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | claimed |
| US-8834909-B2 | Granule baits | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| US-20070071784-A1 | Organic compounds | ELANCO TIERGESUNDHEIT AG (CH) | 2007-03-29 | — | — | US | disclosed |
| EP-1651034-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | disclosed |
| US-4205066-A | Bait compositions for anthropophilic flies | AIRWICK INDUSTRIES, INC. (US) | 1980-05-27 | — | — | US | disclosed |