Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | XIAP | P98170 | 5/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567965 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAXIAPBIRC2NR1H4 | |
| SCHEMBL5569136 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAXIAPBIRC2NR1H4 | |
| SCHEMBL1901039 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL1904488 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL1901041 | 0.83 | ALDH1A1 (0.63) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL6873155 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL3973534 | 0.80 | HTR3E (0.68) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL6023527 | 0.80 | BIRC2 (0.46) | ALDH1A1LMNABIRC2HTR3EHTR3B | |
| SCHEMBL1847071 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAXIAPBIRC2HTR3E | |
| SCHEMBL2249569 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAXIAPBIRC2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100457738-C | Aryloxyphenyl and arylsulfanylphenyl piperazine derivatives | LUNDBECK & CO AS H (DK) | 2009-02-04 | — | — | CN | disclosed |
| EP-1458689-B1 | ARYLOXYPHENYL AND ARYLSULFANYLPHENYL DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-04-11 | — | — | EP | disclosed |
| US-7067501-B2 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-06-27 | — | — | US | disclosed |
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2005-08-04 | — | — | US | disclosed |
| CN-1606548-A | Aryloxyphenyl and Arylthiophenyl Derivatives | LUNDBECK & CO AS H (DK) | 2005-04-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171061-A1 | Aryloxyphenyl and arylsulfanylphenyl derivatives | SLC1A5, SLC6A7, SLC6A19 | ALDH1A1 1022/4885LMNA 4344/4885XIAP 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.