Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666890 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666891 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNAGAAHTTKMT2A | |
| Biphenyl SCHEMBL27953790 | 0.84 | ALDH1A1 (0.62) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666899 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666900 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666956 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666954 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAGAAHTTKMT2A | |
| Aniline SCHEMBL28189429 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL17666958 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAGAAHTTKMT2A | |
| SCHEMBL5564609 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105294527-B | Aryl-substituted formaldehyde or acetophenone thiosemicarbazone derivative and its application as tyrosinase inhibitor | 中国广州分析测试中心 | 2018-02-06 | — | — | CN | claimed |
| EP-3006496-B1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORP (JP) | 2017-07-19 | — | — | EP | claimed |
| EP-3006496-B1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORP (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-20160115296-A1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | BRIDGESTONE CORPORATION (JP) | 2016-04-28 | — | — | US | disclosed |
| EP-3006496-A1 | TIRE RUBBER COMPOSITION AND MANUFACTURING METHOD THEREFOR | Bridgestone Corporation (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-20070059299-A1 | S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-03-15 | — | — | US | disclosed |
| EP-1549611-A2 | S-ADENOSYL METHIONINE DECARBOXYLASE INHIBITION FOR THE TREATMENT OF A HERPES SIMPLEX VIRUS INFECTION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004033417-A2 | S-ADENOSYL METHIONINE DECARBOXYLASE INHIBITION FOR THE TREATMENT OF A HERPES SIMPLEX VIRUS INFECTION | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-04-22 | — | — | WO | disclosed |
| US-4032659-A | ADMINISTERING THIOSEMICARBAZONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070059299-A1 | S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection | AMD1, AHCY, MAT2A | ALDH1A1 361/4885LMNA 4875/4885GAA 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.