Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 9/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569474 | 0.89 | P2RX3 (0.39) | S1PR1P2RX3S1PR3MEN1KMT2A | |
| SCHEMBL2104873 | 0.87 | CENPE (0.51) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL5569134 | 0.83 | CENPE (0.39) | CENPES1PR1P2RX3WDR5KMO | |
| SCHEMBL13626786 | 0.80 | CENPE (0.50) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL3468364 | 0.80 | CENPE (0.50) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL2104831 | 0.80 | CENPE (0.51) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL13161714 | 0.79 | CENPE (0.54) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL3462435 | 0.79 | CENPE (0.54) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL4876587 | 0.79 | S1PR1 (0.39) | CENPES1PR1P2RX3S1PR3S1PR5 | |
| SCHEMBL2104141 | 0.78 | CENPE (0.42) | CENPES1PR1P2RX3S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | CENPE 54/4885S1PR1 2943/4885P2RX3 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.