Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624798 | 0.88 | TAAR1 (0.50) | KMT2AMAOBIDO1TAAR1 | |
| SCHEMBL18003515 | 0.84 | MAOB (0.66) | MAOB | |
| SCHEMBL2267819 | 0.82 | KIF11 (0.55) | MAOBIDO1CA1CA2TAAR1 | |
| SCHEMBL11083312 | 0.80 | LTA4H (0.49) | MAPK14LTA4HMAOBCA1CA2 | |
| SCHEMBL11148692 | 0.79 | CA1 (0.52) | MAPK14LTA4HMAOBIDO1CA1 | |
| SCHEMBL1685383 | 0.79 | CA1 (0.52) | MAPK14LTA4HMAOBIDO1CA1 | |
| SCHEMBL2464598 | 0.79 | MAPK14 (0.42) | MAPK14LTA4HKMT2AMEN1EPHX2 | |
| SCHEMBL5563797 | 0.79 | LTA4H (0.47) | MAPK14LTA4HKMT2AEPHX2MAOB | |
| SCHEMBL29377645 | 0.77 | LTA4H (0.50) | MAPK14LTA4HMAOBIDO1CA1 | |
| SCHEMBL922221 | 0.77 | MAOB (0.69) | MAPK14LTA4HKMT2AMEN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173169-A4 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2007-04-04 | — | — | EP | disclosed |
| EP-1173169-A1 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000057877-A1 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2000-10-05 | — | — | WO | disclosed |