Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30219864 | 0.89 | HTR6 (0.35) | ALDH1A1L3MBTL1NSD2EGFRLMNA | |
| SCHEMBL30318774 | 0.78 | HTR7 (0.41) | ALDH1A1MAPTTDP1KDM4ERAB9A | |
| SCHEMBL1691086 | 0.78 | HTR7 (0.41) | ALDH1A1MAPTTDP1KDM4ERAB9A | |
| SCHEMBL5569714 | 0.77 | MEN1 (0.38) | ALDH1A1MAPTTDP1KDM4ERAB9A | |
| SCHEMBL20718751 | 0.75 | CA1 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8323307 | 0.74 | NPC1 (0.36) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL1574869 | 0.74 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTTDP1KDM4E | |
| SCHEMBL1936383 | 0.72 | ROCK2 (0.43) | ALDH1A1LMNANPSR1 | |
| SCHEMBL20862868 | 0.72 | MAPT (0.47) | ALDH1A1L3MBTL1NSD2EGFRLMNA | |
| SCHEMBL30271318 | 0.71 | MAPT (0.41) | ALDH1A1L3MBTL1NSD2EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215886-A | Compounds and compositions as endosomal Toll-like receptor inhibitors | 诺华股份有限公司 | 2022-10-21 | — | — | CN | disclosed |