Quinoline

Quinoline

SCHEMBL5569889

CCl.c1ccc2ncccc2c1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.85
NR4A2 P43354 1/20 0.54
NPC1 O15118 1/20 0.52
POLB P06746 1/20 0.52
RAB9A P51151 1/20 0.52
CYP3A4 P08684 2/20 0.50
HTT P42858 3/20 0.48
CYP1A2 P05177 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 3/20 0.48
CASP1 P29466 2/20 0.48
TP53 P04637 2/20 0.48
HSP90AA1 P07900 2/20 0.48
TSHR P16473 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
CASP7 P55210 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSP90AB1 P08238 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28105560 1.00 ALDH1A1 (0.85) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL29774014 0.95 ALDH1A1 (0.94) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL9684173 0.92 ALDH1A1 (0.90) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL29822171 0.92 ALDH1A1 (1.00) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL1270969 0.92 ALDH1A1 (1.00) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL29349552 0.92 ALDH1A1 (1.00) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL32661377 0.92 ALDH1A1 (1.00) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL2774 0.92 ALDH1A1 (1.00) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL11311891 0.90 ALDH1A1 (0.85) ALDH1A1NR4A2NPC1POLBRAB9A
Quinoline SCHEMBL1591955 0.90 ALDH1A1 (0.85) ALDH1A1NR4A2NPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108935507-A Agricultural active ingredients and its application 四川利尔作物科学有限公司 2018-12-07 CN claimed
CN-110003118-A The method for preparing carboxylic ester derivative 阿达玛马克西姆股份有限公司 2019-07-12 CN disclosed
CN-109212108-A Gas chromatography-mass spectrometry that is a kind of while measuring three kinds of trace quinolines herbicides in rice and soybean 丁立平 2019-01-15 CN disclosed
CN-108990986-A Use D- napropamide selectively control weeds UPL 有限公司 2018-12-14 CN disclosed
CN-104884062-B N- (substituted) -5-fluoro-4-imino-3-methyl-2-oxo-3, 4-dihydropyrimidine-1 (2h) -carboxamide derivatives 阿达玛马克西姆股份有限公司 2018-11-06 CN disclosed
CN-104994859-B 1- (substituted benzoyl) -5-fluoro-4-imino-3-methyl-3, 4-dihydropyrimidin-2 (1H) -one derivatives 阿达玛马克西姆股份有限公司 2018-10-26 CN disclosed
US-10087530-B2 Corrosion inhibition SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2018-10-02 US disclosed
CN-104661524-B Include the Herbicidal combinations of the fluoro- 6- of the chloro- 5- of 4- amino -3- (the fluoro- 3- methoxyphenyls of the chloro- 2- of 4-) pyridine -2- formic acid 美国陶氏益农公司 2018-09-25 CN disclosed
CN-105519549-B Synergistic herbicidal composition containing penoxsuam and bentazone 陶氏益农公司 2018-08-28 CN disclosed
CN-108391672-A A kind of Herbicidal combinations 江苏龙灯化学有限公司 2018-08-14 CN disclosed
EP-1754693-A1 Process for the production of esters or lactones, and process for the production of peroxides Daicel Chemical Industries, Ltd. (JP) 2007-02-21 EP disclosed
EP-0990631-B1 PROCESS FOR COOXIDIZING ORGANIC COMPOUNDS DAICEL CHEM (JP) 2007-01-24 EP disclosed
EP-1036788-B1 Process for producing sulfonic acids or salts thereof DAICEL CHEM (JP) 2003-06-04 EP disclosed
EP-1070678-B1 PROCESS FOR PRODUCING HYDROGEN PEROXIDE DAICEL CHEM (JP) 2003-05-07 EP disclosed
US-6375922-B1 OXIDATION OF ALCOHOL WITH OXYGEN IN PRESENCE OF (N-HYDROXY-) SUCCINIMIDE DERIVATIVE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-04-23 US disclosed
US-6229023-B1 N-OXY OR HYDROXY CYCLIC IMIDE OXIDATION CATALYST DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2001-05-08 US disclosed
EP-1070678-A1 PROCESS FOR PRODUCING HYDROGEN PEROXIDE Daicel Chemical Industries, Ltd. (JP) 2001-01-24 EP disclosed
US-6143924-A Process for producing organic sulfur acids or salts thereof DAICEL CHEMICAL INDUSTRIES, LTD (JP) 2000-11-07 US disclosed
EP-1036788-A1 Process for producing sulfonic acids or salts thereof Daicel Chemical Industries, Ltd. (JP) 2000-09-20 EP disclosed
EP-0990631-A1 PROCESS FOR COOXIDIZING ORGANIC COMPOUNDS, PROCESS FOR PRODUCING EPOXY COMPOUNDS AND PROCESS FOR PRODUCING ESTERS OR LACTONES Daicel Chemical Industries, Ltd. (JP) 2000-04-05 EP disclosed