Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | CENPE | Q02224 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566639 | 0.91 | CENPE (0.47) | ACACBCENPEXDHS1PR1 | |
| SCHEMBL5566646 | 0.91 | CENPE (0.47) | ACACBCENPEXDHS1PR1 | |
| SCHEMBL5566647 | 0.91 | CENPE (0.47) | ACACBCENPEXDHS1PR1 | |
| SCHEMBL10274283 | 0.86 | CENPE (0.52) | ACACBCENPEXDHALDH1A1HPGD | |
| SCHEMBL13162058 | 0.76 | CENPE (0.64) | CENPEXDHS1PR1 | |
| SCHEMBL3462485 | 0.76 | CENPE (0.64) | CENPEXDHS1PR1 | |
| SCHEMBL14421615 | 0.73 | MME (0.35) | ACACBCENPE | |
| SCHEMBL13456913 | 0.71 | CENPE (0.56) | CENPEXDHALDH1A1HPGDS1PR1 | |
| SCHEMBL2617238 | 0.71 | TAS1R3 (0.43) | ACACBCENPEHPGD | |
| SCHEMBL14873618 | 0.71 | CENPE (0.48) | CENPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | ACACB 903/4885CENPE 54/4885XDH 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.