Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.65 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.61 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556655 | 0.89 | APLNR (0.65) | APLNRCD274PDCD1HTR2AHTR2C | |
| SCHEMBL10141758 | 0.87 | APLNR (0.65) | APLNRMTNR1AMTNR1B | |
| SCHEMBL7768853 | 0.87 | APLNR (0.86) | APLNRHTR2AHTR2CMEN1KMT2A | |
| SCHEMBL22579009 | 0.83 | APLNR (0.57) | APLNRCD274PDCD1HTR2AHTR2C | |
| SCHEMBL30080255 | 0.82 | MTNR1A (0.53) | MTNR1AMTNR1BHTR2AHTR2C | |
| SCHEMBL27764205 | 0.82 | APLNR (0.63) | APLNRCD274PDCD1HTR2AHTR2C | |
| SCHEMBL5096316 | 0.82 | CD274 (0.70) | CD274PDCD1 | |
| SCHEMBL24851928 | 0.82 | APLNR (0.67) | APLNRCD274HTR2AHTR2CMEN1 | |
| SCHEMBL3200678 | 0.82 | APLNR (0.67) | APLNRCD274HTR2AHTR2CMEN1 | |
| SCHEMBL20565881 | 0.81 | APLNR (0.61) | APLNRCD274PDCD1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689708-B1 | N-ACYL-N -BENZYL-ALKYLENDIAMINO DERIVATIVES | NEWRON PHARM SPA (IT) | 2007-06-27 | — | — | EP | disclosed |