Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570351 | 0.87 | BCHE (0.55) | BCHEMEN1KMT2AADRB1ADRB3 | |
| SCHEMBL4904834 | 0.82 | MEN1 (0.47) | BCHEMEN1KMT2APOLBMAPK1 | |
| SCHEMBL2295371 | 0.79 | BCHE (0.64) | BCHELMNAPRMT5WDR77 | |
| SCHEMBL323593 | 0.79 | BCHE (0.64) | BCHELMNAPRMT5WDR77 | |
| SCHEMBL2299217 | 0.79 | BCHE (0.64) | BCHELMNAPRMT5WDR77 | |
| SCHEMBL14421596 | 0.79 | ADRB3 (0.44) | MEN1KMT2ALMNAADRB1ADRB3 | |
| SCHEMBL4775432 | 0.79 | ALDH1A1 (0.46) | BCHEMEN1KMT2APOLBMAPK1 | |
| SCHEMBL27731779 | 0.78 | BCHE (0.63) | BCHEMEN1KMT2ALMNAADRB3 | |
| SCHEMBL2297276 | 0.78 | BCHE (0.63) | BCHEMEN1KMT2ALMNAADRB3 | |
| SCHEMBL2295136 | 0.78 | BCHE (0.63) | BCHEMEN1KMT2ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | claimed |
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | BCHE 3114/4885MEN1 1302/4885KMT2A 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.