Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570353 | 0.82 | BCHE (0.51) | MEN1KMT2APOLBMAPK1NPSR1 | |
| SCHEMBL323594 | 0.79 | BCHE (0.55) | MEN1KMT2APOLBMAPK1NPSR1 | |
| SCHEMBL4884258 | 0.76 | CSNK2A1 (0.55) | MEN1KMT2ANPSR1CSNK2A1 | |
| SCHEMBL5569180 | 0.76 | ALOX5 (0.46) | CSNK2A1 | |
| SCHEMBL4775432 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2APOLBMAPK1NPSR1 | |
| SCHEMBL324109 | 0.75 | KMT2A (0.58) | MEN1KMT2ABCHE | |
| SCHEMBL27569179 | 0.72 | MRGPRX4 (0.51) | MEN1KMT2ACSNK2A1 | |
| SCHEMBL5273185 | 0.71 | BCHE (0.60) | MEN1KMT2APOLBMAPK1NPSR1 | |
| SCHEMBL5269605 | 0.71 | BCHE (0.59) | MEN1KMT2APOLBMAPK1NPSR1 | |
| SCHEMBL4778789 | 0.70 | LTA4H (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | claimed |