Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390293 | 0.80 | KMT2A (0.51) | KMT2APOLBSIGMAR1CA1CA2 | |
| SCHEMBL30965769 | 0.78 | POLB (0.56) | POLBHRH1CCR3SIGMAR1STS | |
| SCHEMBL26681559 | 0.77 | ALDH1A1 (0.56) | KMT2ASIGMAR1CA1CA2MMP1 | |
| SCHEMBL8678905 | 0.76 | KMT2A (0.52) | KMT2ASIGMAR1CA1CA2MMP1 | |
| SCHEMBL4584366 | 0.76 | KDM4E (0.64) | KMT2APOLBLMNATPSAB1 | |
| SCHEMBL1967952 | 0.74 | STS (0.58) | KMT2ASTSCA1CA2MMP1 | |
| SCHEMBL4974210 | 0.74 | TPSAB1 (0.55) | KMT2APOLBSIGMAR1CA2RAB9A | |
| SCHEMBL7412108 | 0.74 | POLB (0.55) | KMT2APOLBSIGMAR1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL4875114 | 0.73 | STS (0.57) | KMT2ASTSCA1CA2MMP1 | |
| SCHEMBL29793208 | 0.73 | DCTPP1 (0.48) | KMT2AP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262197-B2 | Phospholipase C inhibitors for use in treating inflammatory disorders | JANSSEN PHARMACEUTICA, N.V (BE) | 2007-08-28 | — | — | US | disclosed |