SCHEMBL5570883

SCHEMBL5570883

O=C(OO)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 2/20 0.35
MGLL Q99685 4/20 0.34
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17447 0.87 MGLL (0.37) PARLMGLLFAAH
SCHEMBL2139612 0.83 MGLL (0.35) PARLMGLL
Fluorene SCHEMBL23748026 0.80 MAOA (0.42) PARLMGLL
Ethylene Glycol SCHEMBL8522385 0.79 MGLL (0.33) PARLMGLL
SCHEMBL756450 0.79 MGLL (0.36) PARLMGLL
SCHEMBL21228088 0.79 MGLL (0.33) PARLMGLL
SCHEMBL20469204 0.79 CCNE1 (0.38) PARLMGLLFAAH
SCHEMBL28388369 0.77 PARL (0.33) PARLMGLL
SCHEMBL14063664 0.77 MGLL (0.33) MGLL
SCHEMBL865136 0.77 MGLL (0.40) PARLMGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4025301-A1 NONINVASIVE METHOD TO QUANTIFY KIDNEY FUNCTION AND FUNCTIONAL DECLINE The Regents of the University of California (US) 2022-07-13 EP disclosed
WO-2021046339-A1 NONINVASIVE METHOD TO QUANTIFY KIDNEY FUNCTION AND FUNCTIONAL DECLINE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-03-11 WO disclosed
EP-1807118-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS Hollis-Eden Pharmaceuticals Inc. (US) 2007-07-18 EP disclosed
WO-2006110172-A2 STEROID ANALOGS AND CHARACTERIZATION AND TREATMENT METHODS HOLLIS-EDEN PHARMACEUTICALS.INC. (US) 2006-10-19 WO disclosed
EP-0681572-B1 THIAZOLIDINETHIONE-ACTIVATED POLYALKYLENE OXIDES ENZON INC (US) 2001-09-05 EP disclosed
EP-0681572-A1 CYCLIC IMIDE THIONE ACTIVATED POLYALKYLENE OXIDES ENZON, INC. (US) 1995-11-15 EP disclosed
EP-0681572-A4 CYCLIC IMIDE THIONE ACTIVATED POLYALKYLENE OXIDES. ENZON INC (US) 1995-09-22 EP disclosed
US-5405877-A Cyclic imide thione activated polyalkylene oxides ENZON, INC. (US) 1995-04-11 US disclosed
US-5349001-A Cyclic imide thione activated polyalkylene oxides ENZON, INC. (US) 1994-09-20 US disclosed
WO-1994017039-A1 CYCLIC IMIDE THIONE ACTIVATED POLYALKYLENE OXIDES ENZON, INC. (US) 1994-08-04 WO disclosed