Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648181 | 0.80 | NPC1 (0.53) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14382198 | 0.77 | IDO1 (0.44) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12313401 | 0.76 | MAPT (0.55) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28469430 | 0.72 | NAAA (0.47) | MAPTKMT2AMEN1ALDH1A1CA12 | |
| SCHEMBL5792178 | 0.71 | NPC1 (0.43) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7811923 | 0.71 | MAPT (0.43) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22169178 | 0.70 | ALDH1A1 (0.57) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10955276 | 0.70 | KDM1A (0.59) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL304891 | 0.69 | CXCR2 (0.54) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL16763415 | 0.69 | ALDH1A1 (0.55) | MAPTALDH1A1ALOX12GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7258702-B2 | Yellow cationic dyes for dyeing of organic material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| US-20050000034-A1 | Yellow cationic dyes for dyeing of organic material | CIBA SPECIALTY CHEMICALS CORPORATION | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050000034-A1 | Yellow cationic dyes for dyeing of organic material | KRT18, PYCR1, CYC1 | MAPT 955/4885KMT2A 1389/4885MEN1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.