Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 5/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224363 | 0.83 | ALOX15 (0.57) | CYP2C19ALOX15MAPK1HTTDHFR | |
| SCHEMBL5573025 | 0.83 | GABRA1 (0.48) | CYP2C19ALOX15MAPK1HTTDHFR | |
| SCHEMBL3656784 | 0.82 | ALOX15 (0.55) | CYP2C19ALOX15MAPK1HTTDHFR | |
| SCHEMBL5571045 | 0.78 | CYP2C19 (0.41) | CYP2C19ALOX15MAPK1HTTGABRA1 | |
| SCHEMBL20987912 | 0.77 | CYP2C19 (0.38) | CYP2C19ALOX15MAPK1HTTDHFR | |
| SCHEMBL20958233 | 0.74 | ESR1 (0.38) | CYP2C19ALOX15MAPK1HTTDHFR | |
| SCHEMBL17500086 | 0.74 | CYP2C19 (0.49) | CYP2C19ALOX15MAPK1HTTHMGCR | |
| SCHEMBL11183692 | 0.74 | ALOX15 (0.47) | CYP2C19ALOX15MAPK1HTTHMGCR | |
| SCHEMBL1023310 | 0.74 | ESR1 (0.48) | CYP2C19ALOX15MAPK1HTTGABRA1 | |
| SCHEMBL29113876 | 0.74 | DHFR (0.44) | DHFRHMGCRGABRA1GABRB2PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030040594-A1 | Stabilizing high-vinyl polybutadiene | BRIDGESTONE CORP. | 2003-02-27 | — | — | US | claimed |
| EP-3458488-B1 | PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2020-12-30 | — | — | EP | disclosed |
| US-20190185598-A1 | Process For Producing Functionalized Polymers | BRIDGESTONE CORPORATION (JP) | 2019-06-20 | — | — | US | disclosed |
| US-7211619-B2 | Stabilizing high-vinyl polybutadiene | BRIDGESTONE CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |