SCHEMBL20958233

SCHEMBL20958233

CCCc1cc(C(c2cc(CCC)c(O)c(CCC)c2)(C(F)(F)F)C(F)(F)F)cc(CCC)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.38
ESR2 Q92731 5/20 0.38
PGR P06401 1/20 0.36
CYP2C19 P33261 1/20 0.35
HMGCR P04035 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
DHFR P00374 1/20 0.33
PRKCI P41743 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
ALOX5 P09917 2/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987915 0.87 DHFR (0.45) ESR1ESR2PGRGABRA1GABRB2
SCHEMBL29716620 0.87 DHFR (0.45) ESR1ESR2PGRGABRA1GABRB2
SCHEMBL20958240 0.84 PGR (0.31) ESR1ESR2PGR
SCHEMBL20958248 0.84 GABRA1 (0.46) ESR1ESR2PGRCYP2C19ALOX15
SCHEMBL20987912 0.83 CYP2C19 (0.38) ESR1ESR2PGRCYP2C19HMGCR
SCHEMBL3684225 0.80 ESR1 (0.49) ESR1ESR2PGRHMGCRPRKCI
SCHEMBL224363 0.78 ALOX15 (0.57) ESR1ESR2CYP2C19HMGCRALOX15
SCHEMBL2466723 0.78 ESR1 (0.41) ESR1ESR2CYP2C19ALOX15MAPK1
SCHEMBL2469693 0.78 PTPN1 (0.40) ESR1ESR2CYP2C19ALOX15MAPK1
SCHEMBL2466676 0.77 ESR1 (0.38) ESR1ESR2CYP2C19ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779901-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-10-10 US disclosed
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-08-29 US disclosed
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-23 US disclosed
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-16 US disclosed
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 US disclosed
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-18 US disclosed
US-20220250032-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-11 US disclosed
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY 2022-08-04 US disclosed
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-05-10 US disclosed
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-05-10 US disclosed
EP-3706899-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS The Government Of The United States Of America As The Secretary of The Navy (US) 2020-09-16 EP disclosed
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-09 US disclosed
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2019-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11648529-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-20190134601-A1 BISPHENOL HYPERSORBENTS FOR ENHANCED DETECTION OF, OR PROTECTION FROM, HAZARDOUS CHEMICALS SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-20220258126-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-20220250032-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-20220258125-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-20220241750-A1 Bisphenol Hypersorbents for Enhanced Detection of, or Protection From, Hazardous Chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-11654415-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-11779901-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-11738327-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885
US-11325100-B2 Bisphenol hypersorbents for enhanced detection of, or protection from, hazardous chemicals SHBG, GSTP1, GSTA2 ESR1 13/4885ESR2 77/4885PGR 773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.