SCHEMBL5571137

SCHEMBL5571137

Oc1cccc2ccc(N=Nc3ccccn3)c(O)c12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.69
▸ LMNA P02545 2/20 0.69
▸ MAPT P10636 2/20 0.69
▸ OPRK1 P41145 2/20 0.69
▸ HTT P42858 2/20 0.69
▸ SMN1; SMN2 Q16637 2/20 0.69
▸ NPSR1 Q6W5P4 2/20 0.69
▸ TDP1 Q9NUW8 2/20 0.69
▸ L3MBTL1 Q9Y468 2/20 0.69
▸ KMT2A Q03164 2/20 0.69
▸ PKM P14618 1/20 0.69
▸ ALDH1A1 P00352 2/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ POLB P06746 1/20 0.55
▸ HSP90AA1 P07900 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ ALOX12 P18054 1/20 0.55
▸ KCNH2 Q12809 13/20 0.50
▸ RIOK2 Q9BVS4 1/20 0.44
▸ MAOA P21397 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284105 0.82 L3MBTL1 (1.00) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL31621738 0.82 L3MBTL1 (1.00) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL284106 0.82 L3MBTL1 (1.00) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL28263366 0.80 KDM4E (0.65) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL21686428 0.79 MAPT (0.57) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL1933506 0.77 KDM4E (0.61) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL2218613 0.77 KDM4E (0.61) KDM4ELMNAMAPTOPRK1HTT
Water SCHEMBL26684690 0.76 KDM4E (0.59) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL1128642 0.76 LMNA (0.65) KDM4ELMNAMAPTOPRK1HTT
SCHEMBL1128638 0.76 LMNA (0.65) KDM4ELMNAMAPTOPRK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189576-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2007-03-13 — — US disclosed
US-7153696-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-12-26 — — US disclosed
US-7098038-B2 Method for measuring substance and testing piece ARKRAY INC. (JP) 2006-08-29 — — US disclosed
EP-0860695-B1 Method for measuring an analyte and corresponding device ARKRAY INC (JP) 2006-01-04 — — EP disclosed
US-6777243-B2 MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND ARKRAY INC. (JP) 2004-08-17 — — US disclosed
US-20030203503-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-10-30 — — US disclosed
US-20030180183-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-25 — — US disclosed
US-20030175985-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 — — US disclosed
US-20030175984-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-18 — — US disclosed
US-20030166295-A1 Method for measuring substance and testing piece FUKUOKA TAKAO (JP) 2003-09-04 — — US disclosed
EP-0860695-A9 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 2001-10-17 — — EP disclosed
EP-0860695-A1 METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) 1998-08-26 — — EP disclosed
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