Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31246157 | 0.80 | ALDH1A1 (0.53) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL8537413 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MEN1HPGD | |
| SCHEMBL27498342 | 0.78 | ALDH1A1 (0.51) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL7423775 | 0.78 | MMP9 (0.46) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL3741541 | 0.77 | ALDH1A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL19007853 | 0.77 | ALDH1A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL14959576 | 0.77 | ALDH1A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL10047602 | 0.77 | ALDH1A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL20793265 | 0.77 | ALDH1A1 (0.56) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 | |
| SCHEMBL28515555 | 0.77 | SLC15A1 (0.49) | SLC15A1ALDH1A1MAPK1L3MBTL1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539201-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161422-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055144-A1 | AMINE DERIVATIVES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |