Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775200 | 0.87 | L3MBTL1 (0.47) | ALDH1A1KDM4EHPGDPPARGPPARA | |
| SCHEMBL4771091 | 0.86 | EPHX2 (0.43) | ALDH1A1KDM4EEPHX2NR1H4MEN1 | |
| SCHEMBL4777500 | 0.86 | EPHX2 (0.45) | ALDH1A1KDM4EEPHX2NR1H4MEN1 | |
| SCHEMBL4776525 | 0.85 | PPARA (0.47) | EPHX2NR1H4MEN1KMT2APPARG | |
| SCHEMBL4773551 | 0.84 | PPARA (0.45) | ALDH1A1KDM4EEPHX2NR1H4MEN1 | |
| SCHEMBL4776480 | 0.84 | PPARG (0.44) | ALDH1A1KDM4EEPHX2NR1H4MEN1 | |
| SCHEMBL4773543 | 0.83 | EPHX2 (0.42) | ALDH1A1KDM4EHPGDEPHX2NR1H4 | |
| SCHEMBL4773523 | 0.82 | EPHX2 (0.41) | ALDH1A1KDM4EEPHX2NR1H4MEN1 | |
| SCHEMBL4777461 | 0.80 | TSHR (0.55) | ALDH1A1HPGDMEN1KMT2ANAMPT | |
| SCHEMBL4769626 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | claimed |
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135435-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | ALDH1A1 2159/4885KDM4E 3267/4885RCE1 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.