Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420433 | 0.85 | ALDH1A1 (0.49) | KDM4ELMNAALDH1A1HPGDNOTUM | |
| SCHEMBL14833724 | 0.76 | ALDH1A1 (0.41) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL15697552 | 0.75 | RIPK1 (0.62) | DAOGPR35 | |
| SCHEMBL5569527 | 0.74 | ALDH1A1 (0.48) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL5571907 | 0.73 | ALDH1A1 (0.50) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL1823757 | 0.73 | GPR35 (0.52) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL498569 | 0.72 | KDM4E (0.49) | DAOKDM4ELMNAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1825977 | 0.72 | GPR35 (0.51) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL1761399 | 0.72 | ALDH1A1 (0.71) | DAOKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL1780392 | 0.72 | MEN1 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819719-A2 | OLIGONUCLEOTIDE PROBES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006051397-A2 | OLIGONUCLEOTIDE PROBES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2006-05-18 | — | — | WO | disclosed |