Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682635 | 0.83 | — | — | |
| SCHEMBL9660243 | 0.78 | CYP3A4 (0.33) | THRB | |
| SCHEMBL3496906 | 0.78 | MEN1 (0.32) | THRB | |
| SCHEMBL1792660 | 0.77 | — | — | |
| SCHEMBL27584519 | 0.74 | — | — | |
| SCHEMBL16919273 | 0.69 | THRB (0.61) | THRB | |
| SCHEMBL13618125 | 0.69 | THRB (0.38) | THRB | |
| SCHEMBL2867592 | 0.68 | CYP3A4 (0.36) | — | |
| SCHEMBL6389013 | 0.68 | — | — | |
| SCHEMBL7661042 | 0.68 | DNM1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |