Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | GSTA1 | P08263 | 5/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574627 | 0.89 | GSTA1 (0.44) | GSTA1GSTP1LGALS1MEN1KMT2A | |
| SCHEMBL5570767 | 0.88 | GSTA1 (0.45) | GSTA1GSTP1LGALS1MEN1KMT2A | |
| SCHEMBL5574629 | 0.74 | ALDH1A1 (0.47) | GSTA1GSTP1POLBMEN1KMT2A | |
| SCHEMBL8409096 | 0.73 | HDAC6 (0.61) | MAP4K4HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL3908274 | 0.68 | MEN1 (0.63) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL31415856 | 0.66 | HDAC8 (0.72) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6160247 | 0.65 | ALDH1A1 (0.60) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL8410796 | 0.64 | HDAC6 (0.68) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL15650429 | 0.63 | HDAC1 (0.75) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL11302253 | 0.63 | SMN1; SMN2 (0.62) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027075-A1 | Compositions and methods for targeted drug delivery | UNIVERSITY OF CINCINNATI | 2007-02-01 | — | — | US | disclosed |
| WO-2005004795-A2 | COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY | UNIVERSITY OF CINCINNATI (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027075-A1 | Compositions and methods for targeted drug delivery | SLC47A1, SLC47A2, SLC46A1 | MAP4K4 4064/4885HDAC1 4791/4885HDAC6 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.