Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | GSTA1 | P08263 | 5/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 5/20 | 0.41 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574576 | 0.88 | CD69 (0.56) | SMN1; SMN2GSTA1GSTP1CD69PGR | |
| SCHEMBL5574627 | 0.83 | GSTA1 (0.44) | ALDH1A1MEN1KMT2AGSTA1GSTP1 | |
| SCHEMBL5570767 | 0.82 | GSTA1 (0.45) | ALDH1A1MEN1KMT2AGSTA1GSTP1 | |
| SCHEMBL5572030 | 0.74 | MAP4K4 (0.39) | ALDH1A1CYP2C19MEN1KMT2AGSTA1 | |
| SCHEMBL1784315 | 0.72 | ALDH1A1 (0.63) | ALDH1A1GAACYP1A2CYP2C19RAB9A | |
| SCHEMBL5989388 | 0.70 | PTGDR2 (0.54) | ALDH1A1GAACYP1A2CYP2C19RAB9A | |
| SCHEMBL12087531 | 0.69 | MEN1 (0.55) | ALDH1A1GAACYP1A2CYP2C19RAB9A | |
| SCHEMBL711720 | 0.67 | CD69 (0.55) | ALDH1A1GAASMN1; SMN2ABCB1GSTA1 | |
| SCHEMBL18538297 | 0.67 | ALDH1A1 (0.48) | ALDH1A1CYP1A2RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL15517693 | 0.66 | PTGS2 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027075-A1 | Compositions and methods for targeted drug delivery | UNIVERSITY OF CINCINNATI | 2007-02-01 | — | — | US | disclosed |
| WO-2005004795-A2 | COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY | UNIVERSITY OF CINCINNATI (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027075-A1 | Compositions and methods for targeted drug delivery | SLC47A1, SLC47A2, SLC46A1 | ALDH1A1 2662/4885GAA 1209/4885CYP1A2 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.