Biphenyl

Biphenyl

SCHEMBL5572099

C#N.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.75
ATM Q13315 1/20 0.53
MAPK1 P28482 2/20 0.50
TAAR1 Q96RJ0 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NOTUM Q6P988 1/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
SLC22A2 O15244 1/20 0.45
SLC22A1 O15245 1/20 0.45
SLC22A3 O75751 1/20 0.45
SLC6A4 P31645 1/20 0.45
MAOA P21397 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL31021023 1.00 ALDH1A1 (0.75) ALDH1A1ATMMAPK1TAAR1CYP1A2
Tannin Pyrogallol SCHEMBL30277401 0.96 ALDH1A1 (0.69) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL351372 0.87 ALDH1A1 (0.82) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL27713088 0.87 ALDH1A1 (0.82) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL8769842 0.87 ALDH1A1 (0.82) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL9412726 0.87 ALDH1A1 (0.82) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL164 0.87 ALDH1A1 (1.00) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL1358618 0.87 ALDH1A1 (1.00) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL2548048 0.87 ALDH1A1 (1.00) ALDH1A1ATMMAPK1TAAR1CYP1A2
Biphenyl SCHEMBL29008551 0.87 ALDH1A1 (1.00) ALDH1A1ATMMAPK1TAAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063766-A Quaternized covalent triazine organic framework anion exchange membrane and preparation method thereof 黑龙江大学 2024-05-24 CN claimed
CN-117343009-A Preparation method of hydroxyalkyl substituted phenanthridine derivative 湘潭大学 2024-01-05 CN claimed
CN-117304107-A Phenanthridine compound and synthesis method thereof 湘潭大学 2023-12-29 CN claimed
CN-116730916-A Method for synthesizing 6-methylphenidate compound by photocatalysis 安徽理工大学 2023-09-12 CN claimed
CN-112062719-B Method for preparing 6-substituted alkyl phenanthridine compound 安徽理工大学 2023-03-31 CN claimed
CN-114456112-A Synthetic method of benzanthridine derivative 安徽大学 2022-05-10 CN claimed
CN-112062719-A Method for preparing 6-substituted alkyl phenanthridine compound 安徽理工大学 2020-12-11 CN claimed
CN-105348194-B Fluorine-containing phenanthridine derivatives and preparation method thereof 上海大学 2018-04-06 CN claimed
CN-105348194-A Fluorine-containing phenanthridine derivative and preparation method thereof UNIV SHANGHAI 2016-02-24 CN claimed
CN-1042930-A The preparation of rare earth addition and application WU JIAN (CN) 1990-06-13 CN claimed
CN-117343009-B Preparation method of hydroxyalkyl substituted phenanthridine derivative 湘潭大学 2026-03-10 CN disclosed
CN-117304107-B Phenanthridine compound and synthesis method thereof 湘潭大学 2026-03-10 CN disclosed
CN-121378132-A Phenanthridine-6-formaldehyde derivative and preparation method and application thereof 南阳师范学院 2026-01-23 CN disclosed
CN-116730916-B Method for synthesizing 6-methylphenidate compound by photocatalysis 安徽理工大学 2025-09-16 CN disclosed
CN-119409632-A Synthesis method of 6-cyclohexylphenanthridine compound 金华职业技术大学 2025-02-11 CN disclosed
US-20070129434-A1 Analgesics and methods of use ENDO PHARMACEUTICALS INC. 2007-06-07 US disclosed
CN-1612732-A Analgesic and method of use ENDO PHARMACEUTICALS INC (US) 2005-05-04 CN disclosed
EP-1420781-A2 ANALGETIC PYRROLINE DERIVATIVES Endo Pharmaceuticals Inc. (US) 2004-05-26 EP disclosed
WO-2003018004-A2 ANALGETIC PYRROLINE DERIVATIVES ENDO PHARMACEUTICALS, INC. (US) 2003-03-06 WO disclosed
CN-1042930-A The preparation of rare earth addition and application WU JIAN (CN) 1990-06-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129434-A1 Analgesics and methods of use OPRD1, OPRM1, OPRK1 ALDH1A1 162/4885ATM 4860/4885MAPK1 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.