Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569294 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL6405194 | 0.71 | MEN1 (0.47) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5182918 | 0.70 | PDE10A (0.37) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5183502 | 0.67 | MEN1 (0.45) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL6405008 | 0.67 | MAOB (0.45) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL6401844 | 0.66 | GRM5 (0.52) | FGFR1LMNAMAPTMEN1KMT2A | |
| SCHEMBL3816487 | 0.63 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL5052914 | 0.62 | HTR2A (0.78) | HTR2AHTR2C | |
| SCHEMBL29573349 | 0.62 | HTR2A (0.78) | HTR2AHTR2C | |
| SCHEMBL10869110 | 0.62 | RAB9A (0.35) | MAPTKMT2AKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | RPL35, PCNA, MCM5 | FGFR1 4396/4885SMN1; SMN2 4812/4885LMNA 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.