Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052994 | 0.83 | DDX3X (0.66) | SMN1; SMN2GAAHTTRAB9ANPC1 | |
| SCHEMBL2267606 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAHTTRAB9ANPC1 | |
| SCHEMBL30851500 | 0.74 | RAB9A (0.79) | SMN1; SMN2GAARAB9ANPC1MAPT | |
| SCHEMBL27193042 | 0.74 | RAB9A (0.79) | SMN1; SMN2GAARAB9ANPC1MAPT | |
| SCHEMBL6435289 | 0.72 | GRIK1 (0.80) | SMN1; SMN2HTTRAB9ANPC1MAPT | |
| SCHEMBL4719939 | 0.72 | KDR (0.54) | SMN1; SMN2GAAHTTRAB9ANPC1 | |
| SCHEMBL8926778 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2HTTRAB9ANPC1MAPT | |
| SCHEMBL23831319 | 0.71 | GRIK1 (0.62) | SMN1; SMN2GAAHTTRAB9ANPC1 | |
| SCHEMBL30105083 | 0.71 | MEN1 (0.63) | SMN1; SMN2GAAHTTRAB9ANPC1 | |
| SCHEMBL23831849 | 0.71 | MEN1 (0.63) | SMN1; SMN2GAAHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091920-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING THESE, METHOD OF PRODUCTION AND USE | Sanofi-Aventis (FR) | 2009-08-26 | — | — | EP | disclosed |
| WO-2008065282-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING THESE, METHOD OF PRODUCTION AND USE | SANOFI-AVENTIS (FR) | 2008-06-05 | — | — | WO | disclosed |