Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405194 | 0.83 | MEN1 (0.47) | MAOBKDRLMNAMEN1NPC1 | |
| SCHEMBL5569294 | 0.83 | SMN1; SMN2 (0.53) | GRM5GAAKDRLMNAMEN1 | |
| SCHEMBL6405008 | 0.83 | MAOB (0.45) | GRM5MAOBKDRFLT3MEN1 | |
| SCHEMBL19707566 | 0.71 | GAA (0.65) | GRM5MGLLSTING1MAOBGAA | |
| SCHEMBL12870415 | 0.68 | ACHE (0.85) | GRM5ACHEMGLLMAOBKDR | |
| Hydrochloric Acid SCHEMBL1142793 | 0.68 | ACHE (0.83) | GRM5ACHEMGLLMAOBKDR | |
| SCHEMBL9571268 | 0.68 | HRH3 (0.45) | GAAMEN1ALOX15KMT2ACYP3A4 | |
| SCHEMBL29556097 | 0.67 | MAOA (0.69) | MGLLSTING1MAOBGAALMNA | |
| SCHEMBL29556941 | 0.67 | GAA (0.59) | GRM5MGLLSTING1MAOBGAA | |
| SCHEMBL22425108 | 0.67 | GRM5 (0.55) | GRM5STING1KDRLMNAKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000805-A1 | Catalytic hydrogenation process for the manufacture of chlorinated aromatic amines | The Clayton Aniline Company Limited (GB) | 1979-02-21 | — | — | EP | claimed |
| US-20050070528-A1 | Benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors | SOLVAY PHARMACEUTICALS B.V. | 2005-03-31 | — | — | US | disclosed |
| US-20050059658-A1 | Pyridazinone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | TYMP, TPMT, PDXK | GRM5 1493/4885ACHE 3390/4885NPSR1 3627/4885 |
| US-20050070528-A1 | Benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors | OPRL1, ORMDL3, OGFRL1 | GRM5 357/4885ACHE 1387/4885NPSR1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.