Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405194 | 0.83 | MEN1 (0.47) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| SCHEMBL6405008 | 0.83 | MAOB (0.45) | HTTMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6401844 | 0.83 | GRM5 (0.52) | GAANPC1RAB9AMAPTMEN1 | |
| SCHEMBL6404580 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2GAANPC1RAB9AHTT | |
| SCHEMBL5572272 | 0.76 | FGFR1 (0.39) | SMN1; SMN2NPC1RAB9AHTTMAPT | |
| Hydrochloric Acid SCHEMBL1143156 | 0.71 | ACHE (0.72) | SMN1; SMN2GAANPC1RAB9AHTT | |
| SCHEMBL6405326 | 0.69 | PKM (0.48) | SMN1; SMN2GAANPC1RAB9AHTT | |
| SCHEMBL17609477 | 0.68 | RAB9A (1.00) | SMN1; SMN2GAANPC1RAB9AHTT | |
| SCHEMBL6406401 | 0.68 | KDR (0.51) | NPC1HTTMAPTALDH1A1MEN1 | |
| SCHEMBL13568454 | 0.68 | SMN1; SMN2 (0.54) | SMN1; SMN2GAANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583967-B1 | METHOD FOR INHIBITING THE REPLICATION OF HERPES VIRUSES | AICURIS GMBH & CO KG (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | AICURIS GMBH & CO. KG (DE) | 2007-01-04 | — | — | US | disclosed |
| US-20050059658-A1 | Pyridazinone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | TYMP, TPMT, PDXK | SMN1; SMN2 4713/4885GAA 1598/4885NPC1 3414/4885 |
| US-20070004735-A1 | Method for inhibiting the replication of herpes viruses | RPL35, PCNA, MCM5 | SMN1; SMN2 4812/4885GAA 498/4885NPC1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.