Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241011 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1TSHRCDYLSIGMAR1 | |
| SCHEMBL1229651 | 0.77 | CDYL (0.47) | KDM4EALDH1A1TSHRCDYLSIGMAR1 | |
| SCHEMBL14461587 | 0.75 | SIGMAR1 (0.54) | KDM4EALDH1A1TSHRSIGMAR1L3MBTL1 | |
| Oxalic Acid SCHEMBL1229650 | 0.74 | CHEK1 (0.58) | KDM4EALDH1A1TSHRCDYLCYP1A2 | |
| SCHEMBL3807502 | 0.73 | SIGMAR1 (0.62) | KDM4EALDH1A1TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL2185816 | 0.73 | APAF1 (0.49) | KDM4EALDH1A1TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL29387399 | 0.73 | APAF1 (0.49) | KDM4EALDH1A1TSHRSIGMAR1L3MBTL1 | |
| SCHEMBL9363943 | 0.72 | SIGMAR1 (0.44) | KDM4EALDH1A1TSHRCDYLSIGMAR1 | |
| SCHEMBL11690495 | 0.71 | NR4A1 (0.46) | — | |
| Oxalic Acid SCHEMBL6773522 | 0.71 | KDM4E (0.72) | KDM4EALDH1A1TSHRCDYLSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189576-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7153696-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-7098038-B2 | Method for measuring substance and testing piece | ARKRAY INC. (JP) | 2006-08-29 | — | — | US | disclosed |
| EP-0860695-B1 | Method for measuring an analyte and corresponding device | ARKRAY INC (JP) | 2006-01-04 | — | — | EP | disclosed |
| US-6777243-B2 | MEASURING DETECTABLE SUBSTANCE BY USING AQUEOUS REACTION SYSTEM INCLUDING FORMATION REACTION OF DETECTABLE SUBSTANCE BASED ON CHEMICAL REACTION OF ANALYTE CONTAINED IN SAMPLE; REACTING IN PRESENCE OF LAYERED INORGANIC COMPOUND | ARKRAY INC. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20030203503-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-10-30 | — | — | US | disclosed |
| US-20030180183-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-25 | — | — | US | disclosed |
| US-20030175985-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030175984-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-18 | — | — | US | disclosed |
| US-20030166295-A1 | Method for measuring substance and testing piece | FUKUOKA TAKAO (JP) | 2003-09-04 | — | — | US | disclosed |
| EP-0860695-A9 | METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE | KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) | 2001-10-17 | — | — | EP | disclosed |
| EP-0860695-A1 | METHOD OF MEASUREMENT OF MATERIAL AND TESTPIECE | KABUSHIKI KAISHA KYOTO DAIICHI KAGAKU (JP) | 1998-08-26 | — | — | EP | disclosed |