Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | LTK | P29376 | 1/20 | 0.58 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | RAD52 | P43351 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781417 | 0.91 | CHEK1 (0.63) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8379135 | 0.82 | TSHR (0.62) | CHEK1PIM1IDO1LTKLIMK1 | |
| Oxalic Acid SCHEMBL11348295 | 0.78 | CA12 (0.81) | IDO1CA12CA4CA7CA9 | |
| Oxalic Acid SCHEMBL27888753 | 0.78 | CA12 (0.81) | IDO1CA12CA4CA7CA9 | |
| Oxalic Acid SCHEMBL6473515 | 0.77 | CA12 (0.78) | IDO1CA12CA4CA7CA9 | |
| SCHEMBL11669132 | 0.76 | CA12 (0.61) | CA12CA4CA7CA9CA14 | |
| Oxalic Acid SCHEMBL5572818 | 0.74 | KDM4E (0.52) | KDM4EALDH1A1TSHRHPGDKMT2A | |
| Hydrochloric Acid SCHEMBL11668772 | 0.74 | ALDH1A1 (0.62) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL9850535 | 0.74 | ALDH1A1 (0.62) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL9016205 | 0.74 | CA12 (0.62) | CA12CA4CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462441-B1 | METHOD OF DETECTING OXIDES OF NITROGEN | 3M INNOVATIVE PROPERTIES CO (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20150072966-A1 | METHOD OF PROMOTING WOUND HEALING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-12 | — | — | US | disclosed |
| EP-2820428-A1 | METHOD OF PROMOTING WOUND HEALING | 3M Innovative Properties Company (US) | 2015-01-07 | — | — | EP | disclosed |
| US-8617897-B2 | Method of detecting oxides of nitrogen | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-12-31 | — | — | US | disclosed |
| WO-2013130687-A1 | METHOD OF PROMOTING WOUND HEALING | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-09-06 | — | — | WO | disclosed |
| US-8460863-B2 | Dry stick device and method for determining an analyte in a sample | LATTEC I/S (DK) | 2013-06-11 | — | — | US | disclosed |
| EP-1982183-B9 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | LATTEC I S (DK) | 2012-12-12 | — | — | EP | disclosed |
| US-20120308992-A1 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | LATTEC I/S | 2012-12-06 | — | — | US | disclosed |
| EP-1982183-B1 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | LATTEC I S (DK) | 2012-06-27 | — | — | EP | disclosed |
| EP-2462441-A1 | METHOD OF DETECTING OXIDES OF NITROGEN | 3M Innovative Properties Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-8198073-B2 | Dry stick device and method for determining an analyte in a sample | LATTEC I/S (DK) | 2012-06-12 | — | — | US | disclosed |
| US-20120129266-A1 | METHOD OF DETECTING OXIDES OF NITROGEN | 3M INNOVATIVE PROPERTIES COMPANY | 2012-05-24 | — | — | US | disclosed |
| WO-2011017317-A1 | METHOD OF DETECTING OXIDES OF NITROGEN | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20100233723-A1 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | LATTEC I/S (DK) | 2010-09-16 | — | — | US | disclosed |
| EP-1982183-A1 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | Lattec I/S (DK) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007082545-A1 | DRY STICK DEVICE AND METHOD FOR DETERMINING AN ANALYTE IN A SAMPLE | LATTEC I/S (DK) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150072966-A1 | METHOD OF PROMOTING WOUND HEALING | NOS3, NOS1, NOS2 | SLC6A4 3224/4885OPRM1 526/4885CHEK1 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.