Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | METAP1 | P53582 | 3/20 | 0.34 |
| ▸ | CIT | O14578 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449532 | 0.74 | AAK1 (0.35) | METAP2METAP1CITAAK1CTSC | |
| SCHEMBL2492378 | 0.73 | CTSS (0.37) | CTSSCTSLCTSK | |
| SCHEMBL23750067 | 0.65 | METAP2 (0.42) | METAP2METAP1CTSK | |
| SCHEMBL13073340 | 0.62 | EPHX2 (0.61) | — | |
| SCHEMBL7144493 | 0.62 | EPHX2 (0.61) | — | |
| SCHEMBL7358712 | 0.62 | EPHX2 (0.61) | — | |
| SCHEMBL6803053 | 0.61 | MAPT (0.42) | METAP2METAP1CTSSCTSLCTSB | |
| SCHEMBL5842745 | 0.60 | METAP2 (0.48) | METAP2METAP1CIT | |
| SCHEMBL5843085 | 0.60 | METAP2 (0.48) | METAP2METAP1CIT | |
| SCHEMBL29533696 | 0.59 | GLO1 (0.43) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845104-A1 | PAR-2 AGONIST | Kowa Company. Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |