Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575277 | 0.99 | GLA (0.43) | KDM4EEPHX2ADRB3NPC1RAB9A | |
| SCHEMBL5575368 | 0.86 | OPRM1 (0.39) | ADRB3MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL5575374 | 0.82 | KDM4E (0.59) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9350980 | 0.82 | KDM4E (0.59) | KDM4ELMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL11341778 | 0.77 | OPRL1 (0.55) | NPC1RAB9AOPRM1OPRD1OPRK1 | |
| SCHEMBL13712069 | 0.77 | SLC6A2 (0.59) | KDM4EEPHX2NPC1RAB9ASLC6A2 | |
| Hydrochloric Acid SCHEMBL3954682 | 0.76 | SLC6A2 (0.58) | KDM4EEPHX2BCHESLC6A2SLC6A4 | |
| SCHEMBL21539590 | 0.75 | POLB (0.45) | EPHX2LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL18298572 | 0.75 | POLB (0.45) | EPHX2LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL30747365 | 0.75 | OPRL1 (0.56) | OPRM1OPRD1OPRK1OPRL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | KDM4E 3689/4885EPHX2 2054/4885ADRB3 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.