Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575277 | 0.87 | GLA (0.43) | OPRM1OPRD1OPRK1OPRL1ADRB3 | |
| SCHEMBL5573889 | 0.86 | KDM4E (0.45) | OPRM1OPRD1OPRK1OPRL1ADRB3 | |
| SCHEMBL18298572 | 0.73 | POLB (0.45) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21539590 | 0.73 | POLB (0.45) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5848565 | 0.73 | ADRB2 (0.57) | ADRB3ADRB1 | |
| SCHEMBL4598198 | 0.72 | CTSL (0.41) | ADRB3ADRB1 | |
| SCHEMBL9902866 | 0.71 | SLC6A4 (0.49) | ADRB3ADRB1 | |
| SCHEMBL16690960 | 0.71 | SLC6A4 (0.49) | ADRB3ADRB1 | |
| SCHEMBL1565019 | 0.70 | TAAR1 (0.51) | — | |
| SCHEMBL2677605 | 0.69 | OPRL1 (0.59) | OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | OPRM1 205/4885OPRD1 330/4885OPRK1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.