Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL11033740 | 0.86 | TSHR (0.53) | ALDH1A1MEN1KMT2ARAB9ACTSD | |
| Biphenyl SCHEMBL998756 | 0.86 | MGLL (0.48) | ALDH1A1MEN1KMT2ARAB9ACTSD | |
| Biphenyl SCHEMBL11066477 | 0.86 | MGLL (0.48) | ALDH1A1MEN1KMT2ARAB9ACTSD | |
| Biphenyl SCHEMBL27766328 | 0.84 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2ARAB9ACTSD | |
| Benzene SCHEMBL28076350 | 0.82 | CYP1A2 (0.47) | ALDH1A1MEN1KMT2ACTSDMAPT | |
| O-Xylene SCHEMBL27905677 | 0.81 | TSHR (0.53) | ALDH1A1RAB9ACTSDNPC1MAPT | |
| Toluene SCHEMBL11475268 | 0.81 | LMNA (0.58) | ALDH1A1MEN1KMT2ARAB9ACTSD | |
| Biphenyl SCHEMBL4593266 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| Biphenyl SCHEMBL5573670 | 0.79 | ALDH1A1 (0.60) | ALDH1A1RAB9ANPC1CTDSP1MAPT | |
| Biphenyl SCHEMBL335359 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105555761-B | Biphenyl derivatives and process for preparing the same | 东亚ST 株式会社 | 2018-12-11 | — | — | CN | claimed |
| CN-105555761-A | Novel biphenyl derivatives and process for preparing the same | DONG A ST CO LTD | 2016-05-04 | — | — | CN | claimed |
| CN-105531269-A | \"inhibitors of nicotinamide phosphoribosyltransferase, compositions, products and uses thereof\ | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO | 2016-04-27 | — | — | CN | claimed |
| CN-105555761-B | Biphenyl derivatives and process for preparing the same | 东亚ST 株式会社 | 2018-12-11 | — | — | CN | disclosed |
| CN-105555761-A | Novel biphenyl derivatives and process for preparing the same | DONG A ST CO LTD | 2016-05-04 | — | — | CN | disclosed |
| CN-105531269-A | \"inhibitors of nicotinamide phosphoribosyltransferase, compositions, products and uses thereof\ | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO | 2016-04-27 | — | — | CN | disclosed |
| CN-102395563-B | Process for the preparation of biphenyl-2-ylcarbamates | GLAXO GROUP LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-102395563-A | Process for the preparation of biphenyl-2-ylcarbamates | GLAXO GROUP LTD | 2012-03-28 | — | — | CN | disclosed |
| US-20070231467-A1 | METHOD FOR MANUFACTURING LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING ELECTRONIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |