Biphenyl

Biphenyl

SCHEMBL998756

NNC(=O)NN.NNC(=O)NN.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.48
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CTSD P07339 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
PTPN1 P18031 1/20 0.45
PTPN11 Q06124 1/20 0.45
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 2/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL11066477 1.00 MGLL (0.48) MGLLALDH1A1MEN1KMT2ACTSD
Biphenyl SCHEMBL5574503 0.86 ALDH1A1 (0.50) MGLLALDH1A1MEN1KMT2ACTSD
Biphenyl SCHEMBL11033740 0.84 TSHR (0.53) MGLLALDH1A1MEN1KMT2ACTSD
Benzene SCHEMBL27433216 0.83 CYP1A2 (0.44) ALDH1A1MEN1KMT2ACTSDSMN1; SMN2
SCHEMBL28094695 0.82 ESR1 (0.53) MGLLNPC1RAB9AMAPT
Biphenyl SCHEMBL27766328 0.82 SMN1; SMN2 (0.54) ALDH1A1MEN1KMT2ACTSDNPC1
Naphthalene SCHEMBL998754 0.81 MAPT (0.47) ALDH1A1MEN1KMT2ACTSDNPC1
Naphthalene SCHEMBL28096488 0.81 MAPT (0.47) ALDH1A1MEN1KMT2ACTSDNPC1
Benzoic Acid SCHEMBL14938995 0.80 TSHR (0.67) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
Chlorobenzene SCHEMBL27712191 0.80 TSHR (0.52) ALDH1A1MEN1KMT2ACTSDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868102-B2 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced TORAY INDUSTRIES, INC. (JP) 2011-01-11 US disclosed
EP-1602680-B1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES (JP) 2010-12-22 EP disclosed
EP-2258746-A2 A method for producing an aromatic polymer, film, electrolyte membrane and separator Toray Industries, Inc. (JP) 2010-12-08 EP disclosed
US-20100016521-A1 Method for producing a film of an aromatic amide oxadiazole polymer containing an oxadiazole structure and the film so produced MORIYAMA HIDEKI 2010-01-21 US disclosed
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same MORIYAMA HIDEKI 2009-07-16 US disclosed
US-7511112-B2 Aromatic polymer, film, electrolyte membrane and separator TORAY INDUSTRIES, INC. (JP) 2009-03-31 US disclosed
US-20060204812-A1 Aromatic polymer, film, electrolyte membrane and separator MORIYAMA HIDEKI 2006-09-14 US disclosed
EP-1602680-A1 AROMATIC POLYMER, FILM, ELECTROLYTE MEMBRANE AND SEPARATOR TORAY INDUSTRIES, INC. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182171-A1 Compound having oxadiazole structure and a dehydration-cyclization method for producing the same OGFOD1, ODC1, OTC MGLL 1589/4885ALDH1A1 973/4885MEN1 1689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.