Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminocaproic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276135 | 0.78 | MAOA (0.54) | MEN1KMT2ALMNAALDH1A1THRB | |
| Norleucine SCHEMBL29028431 | 0.73 | GRM8 (0.45) | MAOA | |
| Aminocaproic Acid SCHEMBL28412351 | 0.73 | KMT2A (0.55) | MEN1KMT2ALMNAALDH1A1PLG | |
| Naphthalene SCHEMBL6898872 | 0.72 | LMNA (0.68) | MEN1KMT2ALMNAALDH1A1PLG | |
| SCHEMBL7824539 | 0.70 | MAOA (0.51) | MEN1KMT2ALMNAALDH1A1MAOA | |
| Nitroanilide SCHEMBL29280534 | 0.70 | KMT2A (0.50) | MEN1KMT2ALMNAALDH1A1PLG | |
| Aminocaproic Acid SCHEMBL6036956 | 0.69 | KMT2A (0.46) | MEN1KMT2ALMNAALDH1A1PLG | |
| SCHEMBL11705705 | 0.69 | MEN1 (0.51) | MEN1KMT2AALDH1A1SLC6A3MAPT | |
| SCHEMBL28520353 | 0.69 | MAOA (0.43) | MEN1KMT2ALMNAALDH1A1MAOA | |
| Sebacic Acid SCHEMBL15541673 | 0.68 | MAPT (0.52) | MEN1KMT2ALMNAALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160345-A | Azaindole-heptamethine cyanine dye, and synthesis method and application thereof | 大连理工大学 | 2022-10-11 | — | — | CN | disclosed |