SCHEMBL8020102

SCHEMBL8020102

CCOC(CO)(C(=O)CO)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
LMNA P02545 1/20 0.39
OPRM1 P35372 3/20 0.37
DRD3 P35462 2/20 0.37
DRD2 P14416 1/20 0.37
KCNN4 O15554 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
MAPT P10636 2/20 0.35
PIN1 Q13526 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GRIN2D O15399 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5574740 0.83 CES1 (0.49) CYP3A4CYP2D6LMNAKCNN4CYP2C19
SCHEMBL17653676 0.77 CYP2D6 (0.43) CYP3A4CYP2D6LMNAKCNN4CYP2C19
SCHEMBL17653674 0.77 CYP2D6 (0.43) CYP3A4CYP2D6LMNAKCNN4CYP2C19
SCHEMBL27592432 0.75 TAAR1 (0.41) CYP3A4CYP2D6LMNAKCNN4CYP2C19
SCHEMBL1255415 0.73 LMNA (0.50) CYP3A4CYP2D6LMNAOPRM1DRD3
SCHEMBL7648277 0.73 CYP2D6 (0.39) CYP3A4CYP2D6LMNAOPRM1DRD3
SCHEMBL7911425 0.73 CES1 (0.49) CYP3A4CYP2D6LMNAKCNN4CYP2C19
SCHEMBL6053202 0.73 CYP2D6 (0.39) CYP3A4CYP2D6LMNAOPRM1DRD3
SCHEMBL28575352 0.72 OPRM1 (0.46) CYP3A4CYP2D6LMNAOPRM1DRD3
SCHEMBL5509050 0.72 MAPT (0.44) CYP3A4CYP2D6OPRM1CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000045777-A1 COMPOSITION, KIT, METHOD AND DEVICE FOR HAIR TREATMENT DIJK EDDY VAN (BE) 2000-08-10 WO claimed
WO-2000045777-A1 COMPOSITION, KIT, METHOD AND DEVICE FOR HAIR TREATMENT DIJK EDDY VAN (BE) 2000-08-10 WO disclosed