Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | PAFAH1B2 | P68402 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4453587 | 0.91 | HIF1A (0.41) | TSHRFAAHTRPV1HIF1AMEN1 | |
| SCHEMBL11515947 | 0.83 | FAAH (0.46) | FAAHMEN1ALDH1A1MAPTPLA2G4A | |
| SCHEMBL4461275 | 0.81 | AOX1 (0.36) | TSHRHIF1AALDH1A1 | |
| SCHEMBL24354774 | 0.81 | ALDH1A1 (0.46) | TSHRFAAHMEN1ALDH1A1MAPT | |
| SCHEMBL11329622 | 0.81 | FAAH (0.42) | TSHRFAAHMEN1ALDH1A1MAPT | |
| SCHEMBL22750760 | 0.80 | FAAH (0.37) | FAAHMEN1ALDH1A1MAPTPLA2G4A | |
| SCHEMBL17764807 | 0.79 | PPARD (0.47) | TSHRFAAHTRPV1 | |
| SCHEMBL2184370 | 0.78 | FAAH (0.60) | FAAHTRPV1MEN1ALDH1A1MAPT | |
| SCHEMBL2184369 | 0.78 | FAAH (0.60) | FAAHTRPV1MEN1ALDH1A1MAPT | |
| SCHEMBL9000158 | 0.77 | PPARD (0.48) | TSHRFAAHTRPV1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817804-A2 | METHOD FOR SYNTHESIZING LONG-CHAIN PHOSPHONIC ACID DERIVATIVES AND THIOL DERIVATIVES | Qimonda AG (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058858-A2 | METHOD FOR SYNTHESIZING LONG-CHAIN PHOSPHONIC ACID DERIVATIVES AND THIOL DERIVATIVES | QIMONDA AG (DE) | 2006-06-08 | — | — | WO | disclosed |