Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13641800 | 0.89 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL187207 | 0.85 | KDM4E (0.59) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL187208 | 0.85 | KDM4E (0.55) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL12722064 | 0.84 | KDM4E (0.57) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL11633334 | 0.83 | KDM4E (0.56) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL5571188 | 0.81 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL8510279 | 0.81 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL2550199 | 0.81 | KDM4E (0.63) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL5575636 | 0.81 | KDM4E (0.57) | KDM4EMAOBAOC3MRGPRX4KMT2A | |
| SCHEMBL5575640 | 0.81 | KDM4E (0.57) | KDM4EMAOBAOC3MRGPRX4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166730-B2 | Process for the preparation of prostaglandin derivatives | FINE TECH LABORATORIES, LTD (IL) | 2007-01-23 | — | — | US | disclosed |
| US-20050209337-A1 | Process for the preparation of prostaglandin derivatives | FINETECH LABORATORIES LTD | 2005-09-22 | — | — | US | disclosed |
| US-6353000-B1 | INTRAOCULAR HYPERTENSION TREATMENT | ALCON LABORATORIES, INC. | 2002-03-05 | — | — | US | disclosed |
| US-5770759-A | 13,14-DIHYDRO-15-KETO-PGF'S; VASOPRESSORS | R-TECH UENO, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| WO-1998020880-A2 | 11-HALO PROSTAGLANDINS FOR THE TREATMENT OF GLAUCOMA OR OCULAR HYPERTENSION | ALCON LABORATORIES, INC. (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5591887-A | 13,14-DIHYDRO-15-KETO-PGFS | R-TECH UENO, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5221763-A | 13,14-dihydro-15-keto-PGFs and salts | R-TECH UENO, LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5106869-A | Vasopressor activity without ephemeral vasorelaxation; no effect on trachea, intestine | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0289349-B1 | PROSTAGLANDINS OF THE F SERIES | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209337-A1 | Process for the preparation of prostaglandin derivatives | PTGIS, PTGES, PTGIR | KDM4E 4475/4885MAOB 1250/4885AOC3 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.